Does CAPECITABINE Cause Neurotoxicity? 553 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 553 reports of Neurotoxicity have been filed in association with CAPECITABINE (Capecitabine). This represents 0.9% of all adverse event reports for CAPECITABINE.
553
Reports of Neurotoxicity with CAPECITABINE
0.9%
of all CAPECITABINE reports
28
Deaths
70
Hospitalizations
How Dangerous Is Neurotoxicity From CAPECITABINE?
Of the 553 reports, 28 (5.1%) resulted in death, 70 (12.7%) required hospitalization, and 31 (5.6%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CAPECITABINE. However, 553 reports have been filed with the FAERS database.
What Other Side Effects Does CAPECITABINE Cause?
Diarrhoea (9,277)
Nausea (6,248)
Palmar-plantar erythrodysaesthesia syndrome (5,294)
Fatigue (5,018)
Death (4,422)
Vomiting (4,111)
Disease progression (3,808)
Off label use (3,193)
Malignant neoplasm progression (2,425)
Asthenia (2,352)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
BLINATUMOMAB (530)
Which CAPECITABINE Alternatives Have Lower Neurotoxicity Risk?
CAPECITABINE vs CAPIVASERTIB
CAPECITABINE vs CAPLACIZUMAB
CAPECITABINE vs CAPLACIZUMAB-YHDP
CAPECITABINE vs CAPMATINIB
CAPECITABINE vs CAPREOMYCIN