Does NELARABINE Cause Polyneuropathy? 29 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 29 reports of Polyneuropathy have been filed in association with NELARABINE (Nelarabine). This represents 4.0% of all adverse event reports for NELARABINE.
29
Reports of Polyneuropathy with NELARABINE
4.0%
of all NELARABINE reports
1
Deaths
5
Hospitalizations
How Dangerous Is Polyneuropathy From NELARABINE?
Of the 29 reports, 1 (3.4%) resulted in death, 5 (17.2%) required hospitalization, and 2 (6.9%) were considered life-threatening.
Is Polyneuropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NELARABINE. However, 29 reports have been filed with the FAERS database.
What Other Side Effects Does NELARABINE Cause?
Febrile neutropenia (67)
Drug ineffective (50)
Myelopathy (47)
Neurotoxicity (47)
Neuropathy peripheral (45)
Muscular weakness (42)
Sepsis (39)
Peripheral sensory neuropathy (38)
Neutropenia (37)
Off label use (37)
What Other Drugs Cause Polyneuropathy?
DEXAMETHASONE (953)
BORTEZOMIB (890)
PACLITAXEL (741)
OXALIPLATIN (691)
CYCLOPHOSPHAMIDE (686)
FLUOROURACIL (525)
TRASTUZUMAB (478)
CARBOPLATIN (463)
DOXORUBICIN (452)
VINCRISTINE (440)
Which NELARABINE Alternatives Have Lower Polyneuropathy Risk?
NELARABINE vs NELFINAVIR
NELARABINE vs NELVUTAMIG
NELARABINE vs NEMOLIZUMAB
NELARABINE vs NEMOLIZUMAB-ILTO
NELARABINE vs NEOMYCIN