Does PACLITAXEL Cause Polyneuropathy? 741 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 741 reports of Polyneuropathy have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 1.0% of all adverse event reports for PACLITAXEL.
741
Reports of Polyneuropathy with PACLITAXEL
1.0%
of all PACLITAXEL reports
54
Deaths
197
Hospitalizations
How Dangerous Is Polyneuropathy From PACLITAXEL?
Of the 741 reports, 54 (7.3%) resulted in death, 197 (26.6%) required hospitalization, and 17 (2.3%) were considered life-threatening.
Is Polyneuropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 741 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Polyneuropathy?
DEXAMETHASONE (953)
BORTEZOMIB (890)
OXALIPLATIN (691)
CYCLOPHOSPHAMIDE (686)
FLUOROURACIL (525)
TRASTUZUMAB (478)
CARBOPLATIN (463)
DOXORUBICIN (452)
VINCRISTINE (440)
DARATUMUMAB (424)
Which PACLITAXEL Alternatives Have Lower Polyneuropathy Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON