Does VINCRISTINE Cause Polyneuropathy? 440 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 440 reports of Polyneuropathy have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.6% of all adverse event reports for VINCRISTINE.
440
Reports of Polyneuropathy with VINCRISTINE
0.6%
of all VINCRISTINE reports
38
Deaths
139
Hospitalizations
How Dangerous Is Polyneuropathy From VINCRISTINE?
Of the 440 reports, 38 (8.6%) resulted in death, 139 (31.6%) required hospitalization, and 30 (6.8%) were considered life-threatening.
Is Polyneuropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 440 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Polyneuropathy?
DEXAMETHASONE (953)
BORTEZOMIB (890)
PACLITAXEL (741)
OXALIPLATIN (691)
CYCLOPHOSPHAMIDE (686)
FLUOROURACIL (525)
TRASTUZUMAB (478)
CARBOPLATIN (463)
DOXORUBICIN (452)
DARATUMUMAB (424)
Which VINCRISTINE Alternatives Have Lower Polyneuropathy Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE