Does TRASTUZUMAB Cause Polyneuropathy? 478 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 478 reports of Polyneuropathy have been filed in association with TRASTUZUMAB (Trazimera). This represents 1.0% of all adverse event reports for TRASTUZUMAB.
478
Reports of Polyneuropathy with TRASTUZUMAB
1.0%
of all TRASTUZUMAB reports
14
Deaths
125
Hospitalizations
How Dangerous Is Polyneuropathy From TRASTUZUMAB?
Of the 478 reports, 14 (2.9%) resulted in death, 125 (26.2%) required hospitalization, and 6 (1.3%) were considered life-threatening.
Is Polyneuropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 478 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Polyneuropathy?
DEXAMETHASONE (953)
BORTEZOMIB (890)
PACLITAXEL (741)
OXALIPLATIN (691)
CYCLOPHOSPHAMIDE (686)
FLUOROURACIL (525)
CARBOPLATIN (463)
DOXORUBICIN (452)
VINCRISTINE (440)
DARATUMUMAB (424)
Which TRASTUZUMAB Alternatives Have Lower Polyneuropathy Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE