Does NIRAPARIB Cause Intentional underdose? 677 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 677 reports of Intentional underdose have been filed in association with NIRAPARIB (ZEJULA). This represents 3.1% of all adverse event reports for NIRAPARIB.
677
Reports of Intentional underdose with NIRAPARIB
3.1%
of all NIRAPARIB reports
40
Deaths
126
Hospitalizations
How Dangerous Is Intentional underdose From NIRAPARIB?
Of the 677 reports, 40 (5.9%) resulted in death, 126 (18.6%) required hospitalization, and 39 (5.8%) were considered life-threatening.
Is Intentional underdose Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIRAPARIB. However, 677 reports have been filed with the FAERS database.
What Other Side Effects Does NIRAPARIB Cause?
Nausea (5,794)
Fatigue (5,240)
Constipation (4,128)
Platelet count decreased (4,102)
Insomnia (2,861)
Blood pressure increased (2,464)
Headache (2,383)
Off label use (2,213)
Vomiting (2,029)
Carbohydrate antigen 125 increased (1,868)
What Other Drugs Cause Intentional underdose?
BUPRENORPHINE\NALOXONE (1,037)
FLUTICASONE\SALMETEROL (605)
DIMETHYL (364)
LEVODOPA (196)
TECFIDERA (180)
FLUTICASONE FUROATE\VILANTEROL TRIFENATATE (167)
DROXIDOPA (163)
ICOSAPENT ETHYL (145)
FLUTICASONE (144)
ACETAMINOPHEN (135)
Which NIRAPARIB Alternatives Have Lower Intentional underdose Risk?
NIRAPARIB vs NIRMATRELVIR\RITONAVIR
NIRAPARIB vs NIROGACESTAT
NIRAPARIB vs NIROGACESTAT HYDROBROMIDE
NIRAPARIB vs NIRSEVIMAB
NIRAPARIB vs NIRSEVIMAB-ALIP