Intentional underdose: Which Medications Cause It? (6,755 Reports Across 194 Drugs)
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Intentional underdose has been reported as an adverse event with 194 different drugs in the FDA's FAERS database, with 6,755 total reports. 153 of these reports resulted in death.The drugs most commonly associated with Intentional underdose are BUPRENORPHINE\NALOXONE, NIRAPARIB, and FLUTICASONE\SALMETEROL.
6,755
Total Reports
194
Drugs Involved
153
Deaths
919
Hospitalizations
57.3 yrs
Average Patient Age
66.6% / 33.4%
Female / Male
Which Drugs Cause Intentional underdose Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| BUPRENORPHINE\NALOXONE | 1,037 | 4.8% | 13 | 162 | 14 |
| NIRAPARIB | 677 | 3.1% | 40 | 126 | 39 |
| FLUTICASONE\SALMETEROL | 605 | 1.3% | 0 | 60 | 0 |
| DIMETHYL | 364 | 0.4% | 2 | 86 | 1 |
| LEVODOPA | 196 | 3.0% | 3 | 9 | 0 |
| TECFIDERA | 180 | 1.7% | 0 | 8 | 0 |
| FLUTICASONE FUROATE\VILANTEROL TRIFENATATE | 167 | 0.7% | 0 | 13 | 0 |
| DROXIDOPA | 163 | 0.8% | 0 | 4 | 0 |
| ICOSAPENT ETHYL | 145 | 3.8% | 0 | 6 | 1 |
| FLUTICASONE | 144 | 0.5% | 0 | 12 | 0 |
| ACETAMINOPHEN | 135 | 0.1% | 0 | 1 | 0 |
| BUPRENORPHINE | 131 | 0.2% | 1 | 35 | 4 |
| ALBUTEROL | 128 | 0.1% | 1 | 24 | 0 |
| APIXABAN | 121 | 0.1% | 1 | 11 | 4 |
| ENZALUTAMIDE | 105 | 0.2% | 31 | 44 | 6 |
| ADAPALENE | 101 | 0.1% | 0 | 0 | 0 |
| UMECLIDINIUM\VILANTEROL TRIFENATATE | 99 | 0.7% | 0 | 5 | 0 |
| FINGOLIMOD | 79 | 0.1% | 0 | 11 | 2 |
| PREGABALIN | 72 | 0.1% | 0 | 12 | 1 |
| CARBIDOPA\LEVODOPA | 71 | 0.1% | 0 | 9 | 0 |