Does NIRAPARIB Cause Pancytopenia? 199 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 199 reports of Pancytopenia have been filed in association with NIRAPARIB (ZEJULA). This represents 0.9% of all adverse event reports for NIRAPARIB.
199
Reports of Pancytopenia with NIRAPARIB
0.9%
of all NIRAPARIB reports
21
Deaths
126
Hospitalizations
How Dangerous Is Pancytopenia From NIRAPARIB?
Of the 199 reports, 21 (10.6%) resulted in death, 126 (63.3%) required hospitalization, and 54 (27.1%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
Yes, Pancytopenia is listed as a known adverse reaction in the official FDA drug label for NIRAPARIB.
What Other Side Effects Does NIRAPARIB Cause?
Nausea (5,794)
Fatigue (5,240)
Constipation (4,128)
Platelet count decreased (4,102)
Insomnia (2,861)
Blood pressure increased (2,464)
Headache (2,383)
Off label use (2,213)
Vomiting (2,029)
Carbohydrate antigen 125 increased (1,868)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which NIRAPARIB Alternatives Have Lower Pancytopenia Risk?
NIRAPARIB vs NIRMATRELVIR\RITONAVIR
NIRAPARIB vs NIROGACESTAT
NIRAPARIB vs NIROGACESTAT HYDROBROMIDE
NIRAPARIB vs NIRSEVIMAB
NIRAPARIB vs NIRSEVIMAB-ALIP