Does NIVOLUMAB Cause Bone marrow failure? 83 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 83 reports of Bone marrow failure have been filed in association with NIVOLUMAB (OPDIVO). This represents 0.1% of all adverse event reports for NIVOLUMAB.
83
Reports of Bone marrow failure with NIVOLUMAB
0.1%
of all NIVOLUMAB reports
25
Deaths
29
Hospitalizations
How Dangerous Is Bone marrow failure From NIVOLUMAB?
Of the 83 reports, 25 (30.1%) resulted in death, 29 (34.9%) required hospitalization, and 7 (8.4%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIVOLUMAB. However, 83 reports have been filed with the FAERS database.
What Other Side Effects Does NIVOLUMAB Cause?
Death (11,216)
Malignant neoplasm progression (9,363)
Off label use (5,208)
Diarrhoea (4,692)
Fatigue (3,709)
Pyrexia (3,454)
Intentional product use issue (3,297)
Rash (2,816)
Nausea (2,805)
Decreased appetite (2,619)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which NIVOLUMAB Alternatives Have Lower Bone marrow failure Risk?
NIVOLUMAB vs NIVOLUMAB\RELATLIMAB-RMBW
NIVOLUMAB vs NIZATIDINE
NIVOLUMAB vs NOMEGESTROL
NIVOLUMAB vs NORDAZEPAM
NIVOLUMAB vs NOREPINEPHRINE