Does NIVOLUMAB Cause Pathological fracture? 76 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 76 reports of Pathological fracture have been filed in association with NIVOLUMAB (OPDIVO). This represents 0.1% of all adverse event reports for NIVOLUMAB.
76
Reports of Pathological fracture with NIVOLUMAB
0.1%
of all NIVOLUMAB reports
26
Deaths
50
Hospitalizations
How Dangerous Is Pathological fracture From NIVOLUMAB?
Of the 76 reports, 26 (34.2%) resulted in death, 50 (65.8%) required hospitalization, and 6 (7.9%) were considered life-threatening.
Is Pathological fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIVOLUMAB. However, 76 reports have been filed with the FAERS database.
What Other Side Effects Does NIVOLUMAB Cause?
Death (11,216)
Malignant neoplasm progression (9,363)
Off label use (5,208)
Diarrhoea (4,692)
Fatigue (3,709)
Pyrexia (3,454)
Intentional product use issue (3,297)
Rash (2,816)
Nausea (2,805)
Decreased appetite (2,619)
What Other Drugs Cause Pathological fracture?
DENOSUMAB (634)
LENALIDOMIDE (260)
DEXAMETHASONE (201)
ALENDRONATE (200)
ZOLEDRONIC ACID (185)
RISEDRONATE (110)
ADALIMUMAB (93)
LETROZOLE (87)
RITUXIMAB (87)
CYCLOPHOSPHAMIDE (85)
Which NIVOLUMAB Alternatives Have Lower Pathological fracture Risk?
NIVOLUMAB vs NIVOLUMAB\RELATLIMAB-RMBW
NIVOLUMAB vs NIZATIDINE
NIVOLUMAB vs NOMEGESTROL
NIVOLUMAB vs NORDAZEPAM
NIVOLUMAB vs NOREPINEPHRINE