Does OLAPARIB Cause Drug resistance? 86 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 86 reports of Drug resistance have been filed in association with OLAPARIB (Lynparza). This represents 0.5% of all adverse event reports for OLAPARIB.
86
Reports of Drug resistance with OLAPARIB
0.5%
of all OLAPARIB reports
31
Deaths
5
Hospitalizations
How Dangerous Is Drug resistance From OLAPARIB?
Of the 86 reports, 31 (36.0%) resulted in death, 5 (5.8%) required hospitalization, and 1 (1.2%) were considered life-threatening.
Is Drug resistance Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for OLAPARIB. However, 86 reports have been filed with the FAERS database.
What Other Side Effects Does OLAPARIB Cause?
Death (4,378)
Malignant neoplasm progression (1,862)
Nausea (1,582)
Anaemia (1,455)
Fatigue (1,437)
Off label use (777)
Vomiting (642)
Drug ineffective (563)
Diarrhoea (514)
Asthenia (491)
What Other Drugs Cause Drug resistance?
LAMIVUDINE (1,889)
IMATINIB (1,293)
GEFITINIB (1,228)
OSIMERTINIB (1,026)
NEVIRAPINE (862)
PREDNISONE (833)
CYCLOPHOSPHAMIDE (817)
LEVETIRACETAM (798)
METHOTREXATE (765)
TENOFOVIR DISOPROXIL (740)
Which OLAPARIB Alternatives Have Lower Drug resistance Risk?
OLAPARIB vs OLARATUMAB
OLAPARIB vs OLECLUMAB
OLAPARIB vs OLIVE OIL\SOYBEAN OIL
OLAPARIB vs OLMESARTAN
OLAPARIB vs OLMESARTAN MEDOXOMIL