Does PACLITAXEL Cause Adrenal insufficiency? 320 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 320 reports of Adrenal insufficiency have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.4% of all adverse event reports for PACLITAXEL.
320
Reports of Adrenal insufficiency with PACLITAXEL
0.4%
of all PACLITAXEL reports
22
Deaths
185
Hospitalizations
How Dangerous Is Adrenal insufficiency From PACLITAXEL?
Of the 320 reports, 22 (6.9%) resulted in death, 185 (57.8%) required hospitalization, and 22 (6.9%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 320 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PEMBROLIZUMAB (1,270)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
Which PACLITAXEL Alternatives Have Lower Adrenal insufficiency Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON