Does PACLITAXEL Cause Constipation? 1,220 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,220 reports of Constipation have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 1.6% of all adverse event reports for PACLITAXEL.
1,220
Reports of Constipation with PACLITAXEL
1.6%
of all PACLITAXEL reports
166
Deaths
642
Hospitalizations
How Dangerous Is Constipation From PACLITAXEL?
Of the 1,220 reports, 166 (13.6%) resulted in death, 642 (52.6%) required hospitalization, and 55 (4.5%) were considered life-threatening.
Is Constipation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 1,220 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which PACLITAXEL Alternatives Have Lower Constipation Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON