Does PACLITAXEL Cause Hepatitis? 297 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 297 reports of Hepatitis have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.4% of all adverse event reports for PACLITAXEL.
297
Reports of Hepatitis with PACLITAXEL
0.4%
of all PACLITAXEL reports
36
Deaths
125
Hospitalizations
How Dangerous Is Hepatitis From PACLITAXEL?
Of the 297 reports, 36 (12.1%) resulted in death, 125 (42.1%) required hospitalization, and 20 (6.7%) were considered life-threatening.
Is Hepatitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 297 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hepatitis?
METHOTREXATE (1,835)
ACETAMINOPHEN (1,450)
TOCILIZUMAB (1,184)
HYDROXYCHLOROQUINE (1,133)
ADALIMUMAB (1,096)
RITUXIMAB (1,017)
ETANERCEPT (1,013)
LEFLUNOMIDE (997)
PEMBROLIZUMAB (935)
NIVOLUMAB (930)
Which PACLITAXEL Alternatives Have Lower Hepatitis Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON