Does PACLITAXEL Cause Hepatocellular injury? 152 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 152 reports of Hepatocellular injury have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.2% of all adverse event reports for PACLITAXEL.
152
Reports of Hepatocellular injury with PACLITAXEL
0.2%
of all PACLITAXEL reports
18
Deaths
82
Hospitalizations
How Dangerous Is Hepatocellular injury From PACLITAXEL?
Of the 152 reports, 18 (11.8%) resulted in death, 82 (53.9%) required hospitalization, and 15 (9.9%) were considered life-threatening.
Is Hepatocellular injury Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 152 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hepatocellular injury?
ACETAMINOPHEN (1,761)
METHOTREXATE (683)
ATORVASTATIN (610)
SULFAMETHOXAZOLE\TRIMETHOPRIM (415)
ENOXAPARIN (365)
TRAMADOL (349)
AMOXICILLIN (347)
ESOMEPRAZOLE (341)
PANTOPRAZOLE (340)
VINCRISTINE (306)
Which PACLITAXEL Alternatives Have Lower Hepatocellular injury Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON