Does PACLITAXEL Cause Hypophysitis? 110 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 110 reports of Hypophysitis have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.1% of all adverse event reports for PACLITAXEL.
110
Reports of Hypophysitis with PACLITAXEL
0.1%
of all PACLITAXEL reports
8
Deaths
81
Hospitalizations
How Dangerous Is Hypophysitis From PACLITAXEL?
Of the 110 reports, 8 (7.3%) resulted in death, 81 (73.6%) required hospitalization, and 21 (19.1%) were considered life-threatening.
Is Hypophysitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 110 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hypophysitis?
IPILIMUMAB (981)
NIVOLUMAB (755)
PEMBROLIZUMAB (411)
CARBOPLATIN (144)
ATEZOLIZUMAB (125)
BEVACIZUMAB (61)
DURVALUMAB (60)
PEMETREXED (51)
CYCLOPHOSPHAMIDE (38)
LENVATINIB (32)
Which PACLITAXEL Alternatives Have Lower Hypophysitis Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON