Does PACLITAXEL Cause Immune-mediated myocarditis? 58 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 58 reports of Immune-mediated myocarditis have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.1% of all adverse event reports for PACLITAXEL.
58
Reports of Immune-mediated myocarditis with PACLITAXEL
0.1%
of all PACLITAXEL reports
11
Deaths
41
Hospitalizations
How Dangerous Is Immune-mediated myocarditis From PACLITAXEL?
Of the 58 reports, 11 (19.0%) resulted in death, 41 (70.7%) required hospitalization, and 9 (15.5%) were considered life-threatening.
Is Immune-mediated myocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 58 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Immune-mediated myocarditis?
PEMBROLIZUMAB (599)
NIVOLUMAB (444)
IPILIMUMAB (248)
CARBOPLATIN (93)
DURVALUMAB (74)
LENVATINIB (66)
DOXORUBICIN (59)
PEMETREXED (43)
ATEZOLIZUMAB (37)
BEVACIZUMAB (32)
Which PACLITAXEL Alternatives Have Lower Immune-mediated myocarditis Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON