Does PEMETREXED Cause Immune-mediated myocarditis? 43 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 43 reports of Immune-mediated myocarditis have been filed in association with PEMETREXED (Pemetrexed). This represents 0.2% of all adverse event reports for PEMETREXED.
43
Reports of Immune-mediated myocarditis with PEMETREXED
0.2%
of all PEMETREXED reports
13
Deaths
34
Hospitalizations
How Dangerous Is Immune-mediated myocarditis From PEMETREXED?
Of the 43 reports, 13 (30.2%) resulted in death, 34 (79.1%) required hospitalization, and 16 (37.2%) were considered life-threatening.
Is Immune-mediated myocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 43 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Immune-mediated myocarditis?
PEMBROLIZUMAB (599)
NIVOLUMAB (444)
IPILIMUMAB (248)
CARBOPLATIN (93)
DURVALUMAB (74)
LENVATINIB (66)
DOXORUBICIN (59)
PACLITAXEL (58)
ATEZOLIZUMAB (37)
BEVACIZUMAB (32)
Which PEMETREXED Alternatives Have Lower Immune-mediated myocarditis Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE