Does PACLITAXEL Cause Thrombotic microangiopathy? 181 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 181 reports of Thrombotic microangiopathy have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.2% of all adverse event reports for PACLITAXEL.
181
Reports of Thrombotic microangiopathy with PACLITAXEL
0.2%
of all PACLITAXEL reports
26
Deaths
107
Hospitalizations
How Dangerous Is Thrombotic microangiopathy From PACLITAXEL?
Of the 181 reports, 26 (14.4%) resulted in death, 107 (59.1%) required hospitalization, and 31 (17.1%) were considered life-threatening.
Is Thrombotic microangiopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 181 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Thrombotic microangiopathy?
TACROLIMUS (1,982)
MYCOPHENOLATE MOFETIL (820)
CYCLOSPORINE (724)
GEMCITABINE (648)
ECULIZUMAB (636)
CYCLOPHOSPHAMIDE (602)
FLUDARABINE (480)
METHOTREXATE (447)
CARFILZOMIB (350)
METHYLPREDNISOLONE (345)
Which PACLITAXEL Alternatives Have Lower Thrombotic microangiopathy Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON