Does METHOTREXATE Cause Thrombotic microangiopathy? 447 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 447 reports of Thrombotic microangiopathy have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
447
Reports of Thrombotic microangiopathy with METHOTREXATE
0.2%
of all METHOTREXATE reports
159
Deaths
181
Hospitalizations
How Dangerous Is Thrombotic microangiopathy From METHOTREXATE?
Of the 447 reports, 159 (35.6%) resulted in death, 181 (40.5%) required hospitalization, and 32 (7.2%) were considered life-threatening.
Is Thrombotic microangiopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 447 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Thrombotic microangiopathy?
TACROLIMUS (1,982)
MYCOPHENOLATE MOFETIL (820)
CYCLOSPORINE (724)
GEMCITABINE (648)
ECULIZUMAB (636)
CYCLOPHOSPHAMIDE (602)
FLUDARABINE (480)
CARFILZOMIB (350)
METHYLPREDNISOLONE (345)
MELPHALAN (332)
Which METHOTREXATE Alternatives Have Lower Thrombotic microangiopathy Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA