Does MELPHALAN Cause Thrombotic microangiopathy? 332 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 332 reports of Thrombotic microangiopathy have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 2.1% of all adverse event reports for MELPHALAN.
332
Reports of Thrombotic microangiopathy with MELPHALAN
2.1%
of all MELPHALAN reports
61
Deaths
128
Hospitalizations
How Dangerous Is Thrombotic microangiopathy From MELPHALAN?
Of the 332 reports, 61 (18.4%) resulted in death, 128 (38.6%) required hospitalization, and 66 (19.9%) were considered life-threatening.
Is Thrombotic microangiopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 332 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Thrombotic microangiopathy?
TACROLIMUS (1,982)
MYCOPHENOLATE MOFETIL (820)
CYCLOSPORINE (724)
GEMCITABINE (648)
ECULIZUMAB (636)
CYCLOPHOSPHAMIDE (602)
FLUDARABINE (480)
METHOTREXATE (447)
CARFILZOMIB (350)
METHYLPREDNISOLONE (345)
Which MELPHALAN Alternatives Have Lower Thrombotic microangiopathy Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL