Does PATISIRAN Cause Hypervolaemia? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Hypervolaemia have been filed in association with PATISIRAN (Onpattro). This represents 0.3% of all adverse event reports for PATISIRAN.
8
Reports of Hypervolaemia with PATISIRAN
0.3%
of all PATISIRAN reports
1
Deaths
7
Hospitalizations
How Dangerous Is Hypervolaemia From PATISIRAN?
Of the 8 reports, 1 (12.5%) resulted in death, 7 (87.5%) required hospitalization.
Is Hypervolaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PATISIRAN. However, 8 reports have been filed with the FAERS database.
What Other Side Effects Does PATISIRAN Cause?
Death (250)
Product dose omission issue (175)
Fatigue (165)
Infusion related reaction (134)
Hospitalisation (127)
Asthenia (108)
Fall (107)
Intentional dose omission (107)
Cardiac failure (95)
Dyspnoea (87)
What Other Drugs Cause Hypervolaemia?
TREPROSTINIL (580)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (428)
AMBRISENTAN (205)
MACITENTAN (202)
FUROSEMIDE (139)
AMLODIPINE (122)
CYCLOPHOSPHAMIDE (118)
SACUBITRIL\VALSARTAN (115)
TACROLIMUS (100)
PREDNISONE (98)
Which PATISIRAN Alternatives Have Lower Hypervolaemia Risk?
PATISIRAN vs PAXIL
PATISIRAN vs PAZOPANIB
PATISIRAN vs PEANUT
PATISIRAN vs PEG INTERFERON
PATISIRAN vs PEG-INTERFERON ALFA 2A