Does PEGINTERFERON ALFA-2A Cause Cholestasis? 25 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 25 reports of Cholestasis have been filed in association with PEGINTERFERON ALFA-2A (Pegasys). This represents 0.1% of all adverse event reports for PEGINTERFERON ALFA-2A.
25
Reports of Cholestasis with PEGINTERFERON ALFA-2A
0.1%
of all PEGINTERFERON ALFA-2A reports
4
Deaths
11
Hospitalizations
How Dangerous Is Cholestasis From PEGINTERFERON ALFA-2A?
Of the 25 reports, 4 (16.0%) resulted in death, 11 (44.0%) required hospitalization, and 3 (12.0%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGINTERFERON ALFA-2A. However, 25 reports have been filed with the FAERS database.
What Other Side Effects Does PEGINTERFERON ALFA-2A Cause?
Fatigue (3,324)
Nausea (2,832)
Anaemia (2,399)
Headache (2,195)
Rash (1,863)
White blood cell count decreased (1,735)
Pyrexia (1,731)
Insomnia (1,579)
Pruritus (1,470)
Pain (1,320)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which PEGINTERFERON ALFA-2A Alternatives Have Lower Cholestasis Risk?
PEGINTERFERON ALFA-2A vs PEGINTERFERON ALFA-2A OR PEGINTERFERON ALFA-2B
PEGINTERFERON ALFA-2A vs PEGINTERFERON ALFA-2A OR PEGINTERFERON ALFA-2B OR PEGINTERFERON BETA-1A OR PEGINTERFERON LAMBDA-1A
PEGINTERFERON ALFA-2A vs PEGINTERFERON ALFA-2B
PEGINTERFERON ALFA-2A vs PEGINTERFERON BETA-1A
PEGINTERFERON ALFA-2A vs PEGINTRON