Does PEGLOTICASE Cause Methaemoglobinaemia? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Methaemoglobinaemia have been filed in association with PEGLOTICASE (Krystexxa). This represents 0.3% of all adverse event reports for PEGLOTICASE.
10
Reports of Methaemoglobinaemia with PEGLOTICASE
0.3%
of all PEGLOTICASE reports
0
Deaths
10
Hospitalizations
How Dangerous Is Methaemoglobinaemia From PEGLOTICASE?
Of the 10 reports, 10 (100.0%) required hospitalization, and 3 (30.0%) were considered life-threatening.
Is Methaemoglobinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGLOTICASE. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does PEGLOTICASE Cause?
Gout (487)
Blood uric acid increased (359)
Infusion related reaction (284)
Therapeutic response decreased (186)
Dyspnoea (153)
Urticaria (133)
Drug ineffective (131)
Nausea (119)
Pruritus (118)
Rash (116)
What Other Drugs Cause Methaemoglobinaemia?
DAPSONE (322)
LIDOCAINE (221)
ACETAMINOPHEN (186)
BENZOCAINE (162)
RASBURICASE (92)
SULFAMETHOXAZOLE\TRIMETHOPRIM (86)
LIDOCAINE\PRILOCAINE (67)
PRIMAQUINE (56)
HYDROXYCHLOROQUINE (54)
MEROPENEM (46)
Which PEGLOTICASE Alternatives Have Lower Methaemoglobinaemia Risk?
PEGLOTICASE vs PEGUNIGALSIDASE ALFA-IWXJ
PEGLOTICASE vs PEGVALIASE-PQPZ
PEGLOTICASE vs PEGVISOMANT
PEGLOTICASE vs PEGZEREPOETIN ALFA
PEGLOTICASE vs PEMBROLIZUMAB