Does PEMBROLIZUMAB Cause Bone marrow failure? 171 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 171 reports of Bone marrow failure have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
171
Reports of Bone marrow failure with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
35
Deaths
78
Hospitalizations
How Dangerous Is Bone marrow failure From PEMBROLIZUMAB?
Of the 171 reports, 35 (20.5%) resulted in death, 78 (45.6%) required hospitalization, and 19 (11.1%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 171 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which PEMBROLIZUMAB Alternatives Have Lower Bone marrow failure Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G