Does PEMBROLIZUMAB Cause Constipation? 1,043 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,043 reports of Constipation have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 1.2% of all adverse event reports for PEMBROLIZUMAB.
1,043
Reports of Constipation with PEMBROLIZUMAB
1.2%
of all PEMBROLIZUMAB reports
136
Deaths
456
Hospitalizations
How Dangerous Is Constipation From PEMBROLIZUMAB?
Of the 1,043 reports, 136 (13.0%) resulted in death, 456 (43.7%) required hospitalization, and 44 (4.2%) were considered life-threatening.
Is Constipation Listed in the Official Label?
Yes, Constipation is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which PEMBROLIZUMAB Alternatives Have Lower Constipation Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G