Does PEMBROLIZUMAB Cause Epilepsy? 139 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 139 reports of Epilepsy have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
139
Reports of Epilepsy with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
23
Deaths
86
Hospitalizations
How Dangerous Is Epilepsy From PEMBROLIZUMAB?
Of the 139 reports, 23 (16.5%) resulted in death, 86 (61.9%) required hospitalization, and 20 (14.4%) were considered life-threatening.
Is Epilepsy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 139 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Epilepsy?
LEVETIRACETAM (2,546)
LAMOTRIGINE (1,758)
ADALIMUMAB (1,107)
TOPIRAMATE (1,066)
METHOTREXATE (960)
LACOSAMIDE (902)
VALPROATE (878)
CARBAMAZEPINE (869)
RITUXIMAB (846)
CETIRIZINE (837)
Which PEMBROLIZUMAB Alternatives Have Lower Epilepsy Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G