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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Epilepsy: Which Medications Cause It? (21,723 Reports Across 927 Drugs)

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Epilepsy has been reported as an adverse event with 927 different drugs in the FDA's FAERS database, with 21,723 total reports. 2,108 of these reports resulted in death.The drugs most commonly associated with Epilepsy are LEVETIRACETAM, LAMOTRIGINE, and ADALIMUMAB.

21,723
Total Reports
927
Drugs Involved
2,108
Deaths
9,287
Hospitalizations
45.5 yrs
Average Patient Age
55.8% / 44.2%
Female / Male

Which Drugs Cause Epilepsy Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
LEVETIRACETAM 2,546 4.1% 86 794 116
LAMOTRIGINE 1,758 3.7% 561 864 491
ADALIMUMAB 1,107 0.2% 571 699 537
TOPIRAMATE 1,066 3.7% 442 519 411
METHOTREXATE 960 0.4% 648 686 586
LACOSAMIDE 902 4.3% 52 306 33
VALPROATE 878 5.5% 46 279 53
CARBAMAZEPINE 869 3.5% 19 228 35
RITUXIMAB 846 0.5% 679 656 580
CETIRIZINE 837 1.8% 635 569 578
TRAMADOL 817 1.1% 482 589 463
DESOXIMETASONE 771 6.6% 622 531 564
TOCILIZUMAB 769 0.8% 670 612 568
PREDNISONE 749 0.5% 587 615 558
METHYLPREDNISOLONE 723 1.1% 572 555 480
SECUKINUMAB 720 0.5% 626 566 575
DICLOFENAC 715 0.8% 636 582 579
ERENUMAB-AOOE 709 1.4% 543 475 472
INFLIXIMAB 708 0.5% 581 528 540
FOLIC ACID 705 3.1% 616 531 572

View all 927 drugs →

Top 3 Drugs Associated With Epilepsy

2,546 reports
1,758 reports
1,107 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)