Does PEMBROLIZUMAB Cause Haematotoxicity? 152 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 152 reports of Haematotoxicity have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
152
Reports of Haematotoxicity with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
21
Deaths
39
Hospitalizations
How Dangerous Is Haematotoxicity From PEMBROLIZUMAB?
Of the 152 reports, 21 (13.8%) resulted in death, 39 (25.7%) required hospitalization, and 11 (7.2%) were considered life-threatening.
Is Haematotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 152 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Haematotoxicity?
CYCLOPHOSPHAMIDE (1,410)
DOXORUBICIN (1,180)
VINCRISTINE (1,038)
RITUXIMAB (812)
CARBOPLATIN (803)
METHOTREXATE (799)
PREDNISONE (730)
CYTARABINE (701)
ETOPOSIDE (677)
CISPLATIN (668)
Which PEMBROLIZUMAB Alternatives Have Lower Haematotoxicity Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G