Does PEMBROLIZUMAB Cause Hepatic encephalopathy? 75 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 75 reports of Hepatic encephalopathy have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
75
Reports of Hepatic encephalopathy with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
31
Deaths
61
Hospitalizations
How Dangerous Is Hepatic encephalopathy From PEMBROLIZUMAB?
Of the 75 reports, 31 (41.3%) resulted in death, 61 (81.3%) required hospitalization, and 8 (10.7%) were considered life-threatening.
Is Hepatic encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 75 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Hepatic encephalopathy?
ACETAMINOPHEN (562)
RIBAVIRIN (512)
LENVATINIB (502)
RIFAXIMIN (462)
SOFOSBUVIR (360)
BEVACIZUMAB (210)
LEDIPASVIR\SOFOSBUVIR (180)
ATEZOLIZUMAB (178)
SORAFENIB (169)
DACLATASVIR (165)
Which PEMBROLIZUMAB Alternatives Have Lower Hepatic encephalopathy Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G