Does PEMBROLIZUMAB Cause Pruritus? 1,336 Reports in FDA Database

Q: Does PEMBROLIZUMAB cause Pruritus?

1,336 reports of Pruritus have been filed with the FDA for PEMBROLIZUMAB, representing 1.6% of all PEMBROLIZUMAB adverse event reports.

Q: How dangerous is Pruritus from PEMBROLIZUMAB?

Of 1,336 reports, 70 (5.2%) resulted in death and 369 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 1,336 reports of Pruritus have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 1.6% of all adverse event reports for PEMBROLIZUMAB.

1,336

Reports of Pruritus with PEMBROLIZUMAB

1.6%

of all PEMBROLIZUMAB reports

Deaths

369

Hospitalizations

How Dangerous Is Pruritus From PEMBROLIZUMAB?

Of the 1,336 reports, 70 (5.2%) resulted in death, 369 (27.6%) required hospitalization, and 35 (2.6%) were considered life-threatening.

Is Pruritus Listed in the Official Label?

Yes, Pruritus is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.

What Other Side Effects Does PEMBROLIZUMAB Cause?

Malignant neoplasm progression (10,111) Death (4,744) Diarrhoea (4,251) Fatigue (3,833) Off label use (3,416) Product use in unapproved indication (3,191) Pyrexia (3,155) Rash (2,900) Nausea (2,670) Decreased appetite (2,486)

What Other Drugs Cause Pruritus?

DUPILUMAB (44,279) ADAPALENE (12,072) ADALIMUMAB (9,644) AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439) SECUKINUMAB (8,755) ETANERCEPT (8,047) METHOTREXATE (7,526) LENALIDOMIDE (6,304) TOCILIZUMAB (5,973) RITUXIMAB (5,548)

Which PEMBROLIZUMAB Alternatives Have Lower Pruritus Risk?

PEMBROLIZUMAB vs PEMETREXED PEMBROLIZUMAB vs PEMIGATINIB PEMBROLIZUMAB vs PENICILLAMINE PEMBROLIZUMAB vs PENICILLIN PEMBROLIZUMAB vs PENICILLIN G

PEMBROLIZUMAB Full Profile All Pruritus Reports All Drugs Causing Pruritus PEMBROLIZUMAB Demographics