Does PEMETREXED Cause Hyperpyrexia? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Hyperpyrexia have been filed in association with PEMETREXED (Pemetrexed). This represents 0.1% of all adverse event reports for PEMETREXED.
27
Reports of Hyperpyrexia with PEMETREXED
0.1%
of all PEMETREXED reports
3
Deaths
14
Hospitalizations
How Dangerous Is Hyperpyrexia From PEMETREXED?
Of the 27 reports, 3 (11.1%) resulted in death, 14 (51.9%) required hospitalization, and 3 (11.1%) were considered life-threatening.
Is Hyperpyrexia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Hyperpyrexia?
TRASTUZUMAB (146)
RITUXIMAB (139)
CYCLOPHOSPHAMIDE (133)
PACLITAXEL (100)
ZOLEDRONIC ACID (96)
OXALIPLATIN (94)
CARBOPLATIN (73)
GEMCITABINE (72)
VINCRISTINE (69)
DABRAFENIB (68)
Which PEMETREXED Alternatives Have Lower Hyperpyrexia Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE