Does PEMETREXED Cause Hyponatraemia? 184 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 184 reports of Hyponatraemia have been filed in association with PEMETREXED (Pemetrexed). This represents 0.8% of all adverse event reports for PEMETREXED.
184
Reports of Hyponatraemia with PEMETREXED
0.8%
of all PEMETREXED reports
23
Deaths
121
Hospitalizations
How Dangerous Is Hyponatraemia From PEMETREXED?
Of the 184 reports, 23 (12.5%) resulted in death, 121 (65.8%) required hospitalization, and 23 (12.5%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 184 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which PEMETREXED Alternatives Have Lower Hyponatraemia Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE