Does PEMETREXED Cause Immune-mediated enterocolitis? 129 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 129 reports of Immune-mediated enterocolitis have been filed in association with PEMETREXED (Pemetrexed). This represents 0.6% of all adverse event reports for PEMETREXED.
129
Reports of Immune-mediated enterocolitis with PEMETREXED
0.6%
of all PEMETREXED reports
30
Deaths
87
Hospitalizations
How Dangerous Is Immune-mediated enterocolitis From PEMETREXED?
Of the 129 reports, 30 (23.3%) resulted in death, 87 (67.4%) required hospitalization, and 19 (14.7%) were considered life-threatening.
Is Immune-mediated enterocolitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 129 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Immune-mediated enterocolitis?
NIVOLUMAB (1,289)
IPILIMUMAB (988)
PEMBROLIZUMAB (858)
CARBOPLATIN (307)
PACLITAXEL (188)
DURVALUMAB (165)
ATEZOLIZUMAB (156)
LENVATINIB (143)
BEVACIZUMAB (92)
TREMELIMUMAB\TREMELIMUMAB-ACTL (63)
Which PEMETREXED Alternatives Have Lower Immune-mediated enterocolitis Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE