Immune-mediated enterocolitis: Which Medications Cause It? (2,862 Reports Across 85 Drugs)
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Immune-mediated enterocolitis has been reported as an adverse event with 85 different drugs in the FDA's FAERS database, with 2,862 total reports. 357 of these reports resulted in death.The drugs most commonly associated with Immune-mediated enterocolitis are NIVOLUMAB, IPILIMUMAB, and PEMBROLIZUMAB.
2,862
Total Reports
85
Drugs Involved
357
Deaths
1,576
Hospitalizations
63.6 yrs
Average Patient Age
41.3% / 58.7%
Female / Male
Which Drugs Cause Immune-mediated enterocolitis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| NIVOLUMAB | 1,289 | 1.5% | 111 | 669 | 122 |
| IPILIMUMAB | 988 | 2.7% | 73 | 504 | 86 |
| PEMBROLIZUMAB | 858 | 1.0% | 150 | 560 | 81 |
| CARBOPLATIN | 307 | 0.4% | 40 | 214 | 44 |
| PACLITAXEL | 188 | 0.2% | 25 | 128 | 27 |
| DURVALUMAB | 165 | 1.0% | 40 | 91 | 31 |
| ATEZOLIZUMAB | 156 | 0.5% | 23 | 89 | 8 |
| LENVATINIB | 143 | 0.4% | 15 | 110 | 12 |
| PEMETREXED | 129 | 0.6% | 30 | 87 | 19 |
| BEVACIZUMAB | 92 | 0.1% | 17 | 40 | 4 |
| TREMELIMUMAB\TREMELIMUMAB-ACTL | 63 | 5.4% | 18 | 40 | 19 |
| CISPLATIN | 60 | 0.1% | 5 | 33 | 6 |
| PREDNISOLONE | 60 | 0.1% | 15 | 37 | 10 |
| INFLIXIMAB | 59 | 0.0% | 9 | 38 | 8 |
| TREMELIMUMAB | 56 | 2.4% | 13 | 34 | 9 |
| ETOPOSIDE | 55 | 0.1% | 3 | 38 | 22 |
| CYCLOPHOSPHAMIDE | 47 | 0.0% | 1 | 36 | 20 |
| CILTACABTAGENE AUTOLEUCEL | 46 | 1.2% | 10 | 13 | 2 |
| CABOZANTINIB S-MALATE | 44 | 0.1% | 2 | 21 | 4 |
| VEDOLIZUMAB | 41 | 0.1% | 1 | 23 | 6 |