Does PEMETREXED Cause Immune-mediated nephritis? 25 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 25 reports of Immune-mediated nephritis have been filed in association with PEMETREXED (Pemetrexed). This represents 0.1% of all adverse event reports for PEMETREXED.
25
Reports of Immune-mediated nephritis with PEMETREXED
0.1%
of all PEMETREXED reports
2
Deaths
7
Hospitalizations
How Dangerous Is Immune-mediated nephritis From PEMETREXED?
Of the 25 reports, 2 (8.0%) resulted in death, 7 (28.0%) required hospitalization, and 1 (4.0%) were considered life-threatening.
Is Immune-mediated nephritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 25 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Immune-mediated nephritis?
NIVOLUMAB (136)
PEMBROLIZUMAB (128)
IPILIMUMAB (91)
CARBOPLATIN (52)
PACLITAXEL (31)
DURVALUMAB (17)
ATEZOLIZUMAB (15)
LENVATINIB (11)
CYCLOPHOSPHAMIDE (9)
AXITINIB (8)
Which PEMETREXED Alternatives Have Lower Immune-mediated nephritis Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE