Immune-mediated nephritis: Which Medications Cause It? (342 Reports Across 26 Drugs)
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Immune-mediated nephritis has been reported as an adverse event with 26 different drugs in the FDA's FAERS database, with 342 total reports. 36 of these reports resulted in death.The drugs most commonly associated with Immune-mediated nephritis are NIVOLUMAB, PEMBROLIZUMAB, and IPILIMUMAB.
342
Total Reports
26
Drugs Involved
36
Deaths
183
Hospitalizations
64.1 yrs
Average Patient Age
41.4% / 58.6%
Female / Male
Which Drugs Cause Immune-mediated nephritis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| NIVOLUMAB | 136 | 0.2% | 6 | 71 | 19 |
| PEMBROLIZUMAB | 128 | 0.2% | 14 | 57 | 8 |
| IPILIMUMAB | 91 | 0.3% | 5 | 51 | 12 |
| CARBOPLATIN | 52 | 0.1% | 4 | 26 | 3 |
| PACLITAXEL | 31 | 0.0% | 5 | 23 | 4 |
| PEMETREXED | 25 | 0.1% | 2 | 7 | 1 |
| DURVALUMAB | 17 | 0.1% | 9 | 11 | 1 |
| ATEZOLIZUMAB | 15 | 0.0% | 2 | 8 | 0 |
| LENVATINIB | 11 | 0.0% | 1 | 6 | 0 |
| CYCLOPHOSPHAMIDE | 9 | 0.0% | 0 | 3 | 1 |
| AXITINIB | 8 | 0.1% | 0 | 4 | 0 |
| OXALIPLATIN | 8 | 0.0% | 0 | 7 | 0 |
| CISPLATIN | 7 | 0.0% | 1 | 5 | 1 |
| DOXORUBICIN | 7 | 0.0% | 0 | 3 | 1 |
| AMOXICILLIN | 6 | 0.0% | 0 | 6 | 0 |
| BEVACIZUMAB | 6 | 0.0% | 2 | 3 | 0 |
| CABOZANTINIB | 6 | 0.2% | 1 | 6 | 2 |
| FLUOROURACIL | 6 | 0.0% | 0 | 5 | 1 |
| PANTOPRAZOLE | 6 | 0.0% | 4 | 5 | 1 |
| TISLELIZUMAB | 6 | 0.1% | 0 | 3 | 0 |