Does PEMETREXED Cause Second primary malignancy? 29 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 29 reports of Second primary malignancy have been filed in association with PEMETREXED (Pemetrexed). This represents 0.1% of all adverse event reports for PEMETREXED.
29
Reports of Second primary malignancy with PEMETREXED
0.1%
of all PEMETREXED reports
5
Deaths
9
Hospitalizations
How Dangerous Is Second primary malignancy From PEMETREXED?
Of the 29 reports, 5 (17.2%) resulted in death, 9 (31.0%) required hospitalization, and 1 (3.4%) were considered life-threatening.
Is Second primary malignancy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 29 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Second primary malignancy?
CYCLOPHOSPHAMIDE (1,247)
DOXORUBICIN (1,151)
VINCRISTINE (908)
IMATINIB (763)
PALBOCICLIB (658)
RITUXIMAB (646)
RUXOLITINIB (611)
ETOPOSIDE (573)
PREDNISONE (517)
OCTREOTIDE (496)
Which PEMETREXED Alternatives Have Lower Second primary malignancy Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE