Does PERTUZUMAB Cause Appendicitis? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Appendicitis have been filed in association with PERTUZUMAB (PERJETA). This represents 0.2% of all adverse event reports for PERTUZUMAB.
33
Reports of Appendicitis with PERTUZUMAB
0.2%
of all PERTUZUMAB reports
12
Deaths
32
Hospitalizations
How Dangerous Is Appendicitis From PERTUZUMAB?
Of the 33 reports, 12 (36.4%) resulted in death, 32 (97.0%) required hospitalization, and 1 (3.0%) were considered life-threatening.
Is Appendicitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 33 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Appendicitis?
ADALIMUMAB (372)
METRONIDAZOLE (291)
GABAPENTIN (281)
ONDANSETRON (278)
SIMVASTATIN (270)
CEFTRIAXONE (268)
HYDROMORPHONE (265)
ALBUTEROL (264)
ALLOPURINOL (264)
LANSOPRAZOLE (263)
Which PERTUZUMAB Alternatives Have Lower Appendicitis Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN