Does PERTUZUMAB Cause Clostridium difficile colitis? 24 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Clostridium difficile colitis have been filed in association with PERTUZUMAB (PERJETA). This represents 0.1% of all adverse event reports for PERTUZUMAB.
24
Reports of Clostridium difficile colitis with PERTUZUMAB
0.1%
of all PERTUZUMAB reports
6
Deaths
21
Hospitalizations
How Dangerous Is Clostridium difficile colitis From PERTUZUMAB?
Of the 24 reports, 6 (25.0%) resulted in death, 21 (87.5%) required hospitalization, and 2 (8.3%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 24 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which PERTUZUMAB Alternatives Have Lower Clostridium difficile colitis Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN