Does PERTUZUMAB Cause Thrombotic microangiopathy? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Thrombotic microangiopathy have been filed in association with PERTUZUMAB (PERJETA). This represents 0.1% of all adverse event reports for PERTUZUMAB.
26
Reports of Thrombotic microangiopathy with PERTUZUMAB
0.1%
of all PERTUZUMAB reports
1
Deaths
10
Hospitalizations
How Dangerous Is Thrombotic microangiopathy From PERTUZUMAB?
Of the 26 reports, 1 (3.8%) resulted in death, 10 (38.5%) required hospitalization, and 13 (50.0%) were considered life-threatening.
Is Thrombotic microangiopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 26 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Thrombotic microangiopathy?
TACROLIMUS (1,982)
MYCOPHENOLATE MOFETIL (820)
CYCLOSPORINE (724)
GEMCITABINE (648)
ECULIZUMAB (636)
CYCLOPHOSPHAMIDE (602)
FLUDARABINE (480)
METHOTREXATE (447)
CARFILZOMIB (350)
METHYLPREDNISOLONE (345)
Which PERTUZUMAB Alternatives Have Lower Thrombotic microangiopathy Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN