Does PHENYTOIN Cause Hypothyroidism? 56 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 56 reports of Hypothyroidism have been filed in association with PHENYTOIN (PHENYTOIN SODIUM). This represents 0.4% of all adverse event reports for PHENYTOIN.
56
Reports of Hypothyroidism with PHENYTOIN
0.4%
of all PHENYTOIN reports
3
Deaths
42
Hospitalizations
How Dangerous Is Hypothyroidism From PHENYTOIN?
Of the 56 reports, 3 (5.4%) resulted in death, 42 (75.0%) required hospitalization, and 2 (3.6%) were considered life-threatening.
Is Hypothyroidism Listed in the Official Label?
Yes, Hypothyroidism is listed as a known adverse reaction in the official FDA drug label for PHENYTOIN.
What Other Side Effects Does PHENYTOIN Cause?
Drug ineffective (2,753)
Seizure (1,907)
Toxicity to various agents (1,248)
Drug hypersensitivity (898)
Off label use (852)
Drug interaction (772)
Drug reaction with eosinophilia and systemic symptoms (673)
Status epilepticus (544)
Fall (436)
Rash (414)
What Other Drugs Cause Hypothyroidism?
PEMBROLIZUMAB (2,326)
LEVOTHYROXINE (2,107)
NIVOLUMAB (1,939)
LENVATINIB (1,375)
ATEZOLIZUMAB (881)
ALBUTEROL (877)
CARBOPLATIN (830)
IPILIMUMAB (770)
AMIODARONE (764)
PREDNISONE (739)
Which PHENYTOIN Alternatives Have Lower Hypothyroidism Risk?
PHENYTOIN vs PHLEUM PRATENSE POLLEN
PHENYTOIN vs PHLOROGLUCINOL
PHENYTOIN vs PHLOROGLUCINOL\1,3,5-TRIMETHOXYBENZENE
PHENYTOIN vs PHOLCODINE
PHENYTOIN vs PHOSPHORUS