PIRFENIDONE for Osteoarthritis: Side Effects & Safety Data
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There are 7 adverse event reports in the FDA FAERS database where PIRFENIDONE was used for Osteoarthritis.
Most Reported Side Effects for PIRFENIDONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 7,221 | 19.0% | 7,159 | 291 |
| Nausea | 4,944 | 13.0% | 220 | 690 |
| Fatigue | 3,597 | 9.5% | 198 | 590 |
| Decreased appetite | 3,126 | 8.2% | 230 | 564 |
| Diarrhoea | 3,026 | 8.0% | 129 | 462 |
| Dyspnoea | 2,526 | 6.7% | 351 | 1,099 |
| Weight decreased | 2,113 | 5.6% | 203 | 424 |
| Dizziness | 2,027 | 5.3% | 96 | 359 |
| Rash | 1,982 | 5.2% | 70 | 185 |
| Cough | 1,692 | 4.5% | 139 | 428 |
| Vomiting | 1,673 | 4.4% | 66 | 303 |
| Pneumonia | 1,646 | 4.3% | 304 | 1,194 |
| Abdominal discomfort | 1,625 | 4.3% | 63 | 217 |
| Abdominal pain upper | 1,460 | 3.9% | 47 | 195 |
| Off label use | 1,362 | 3.6% | 175 | 187 |
Other Indications for PIRFENIDONE
Idiopathic pulmonary fibrosis (27,590)
Product used for unknown indication (4,961)
Pulmonary fibrosis (3,063)
Interstitial lung disease (1,657)
Pulmonary arterial hypertension (210)
Chronic obstructive pulmonary disease (115)
Pneumonia (114)
Idiopathic interstitial pneumonia (94)
Pulmonary hypertension (92)
Hypoxia (71)
Other Drugs Used for Osteoarthritis
DICLOFENAC (1,696)
CELECOXIB (1,287)
ETANERCEPT (1,048)
IBUPROFEN (803)
DENOSUMAB (728)
TOFACITINIB (694)
ADALIMUMAB (686)
NAPROXEN (636)
PREGABALIN (450)
TRIAMCINOLONE ACETONIDE (423)