Does PONATINIB Cause Thrombotic microangiopathy? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Thrombotic microangiopathy have been filed in association with PONATINIB (Iclusig). This represents 0.2% of all adverse event reports for PONATINIB.
20
Reports of Thrombotic microangiopathy with PONATINIB
0.2%
of all PONATINIB reports
6
Deaths
5
Hospitalizations
How Dangerous Is Thrombotic microangiopathy From PONATINIB?
Of the 20 reports, 6 (30.0%) resulted in death, 5 (25.0%) required hospitalization, and 2 (10.0%) were considered life-threatening.
Is Thrombotic microangiopathy Listed in the Official Label?
Yes, Thrombotic microangiopathy is listed as a known adverse reaction in the official FDA drug label for PONATINIB.
What Other Side Effects Does PONATINIB Cause?
Death (1,735)
Off label use (1,071)
Product dose omission issue (817)
Fatigue (687)
Rash (639)
Headache (553)
Pyrexia (542)
Nausea (466)
Hospitalisation (459)
Constipation (435)
What Other Drugs Cause Thrombotic microangiopathy?
TACROLIMUS (1,982)
MYCOPHENOLATE MOFETIL (820)
CYCLOSPORINE (724)
GEMCITABINE (648)
ECULIZUMAB (636)
CYCLOPHOSPHAMIDE (602)
FLUDARABINE (480)
METHOTREXATE (447)
CARFILZOMIB (350)
METHYLPREDNISOLONE (345)
Which PONATINIB Alternatives Have Lower Thrombotic microangiopathy Risk?
PONATINIB vs PONATINIB\PONATINIB
PONATINIB vs PONESIMOD
PONATINIB vs PORACTANT ALFA
PONATINIB vs PORFIMER
PONATINIB vs POSACONAZOLE