Does POSACONAZOLE Cause Cholestasis? 133 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 133 reports of Cholestasis have been filed in association with POSACONAZOLE (POSACONAZOLE). This represents 2.3% of all adverse event reports for POSACONAZOLE.
133
Reports of Cholestasis with POSACONAZOLE
2.3%
of all POSACONAZOLE reports
20
Deaths
92
Hospitalizations
How Dangerous Is Cholestasis From POSACONAZOLE?
Of the 133 reports, 20 (15.0%) resulted in death, 92 (69.2%) required hospitalization, and 3 (2.3%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for POSACONAZOLE. However, 133 reports have been filed with the FAERS database.
What Other Side Effects Does POSACONAZOLE Cause?
Drug ineffective (785)
Product use in unapproved indication (661)
Off label use (430)
Drug interaction (383)
Death (369)
Condition aggravated (214)
Pyrexia (185)
Neutropenia (181)
Product use issue (181)
Febrile neutropenia (178)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which POSACONAZOLE Alternatives Have Lower Cholestasis Risk?
POSACONAZOLE vs POTASSIUM
POSACONAZOLE vs POTASSIUM, DIBASIC
POSACONAZOLE vs POTASSIUM IODIDE
POSACONAZOLE vs POTASSIUM, MONOBASIC
POSACONAZOLE vs POTASSIUM\SODIUM FLUORIDE