Does PROPOFOL Cause Cholestasis? 74 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 74 reports of Cholestasis have been filed in association with PROPOFOL (Propofol). This represents 0.5% of all adverse event reports for PROPOFOL.
74
Reports of Cholestasis with PROPOFOL
0.5%
of all PROPOFOL reports
12
Deaths
45
Hospitalizations
How Dangerous Is Cholestasis From PROPOFOL?
Of the 74 reports, 12 (16.2%) resulted in death, 45 (60.8%) required hospitalization, and 4 (5.4%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PROPOFOL. However, 74 reports have been filed with the FAERS database.
What Other Side Effects Does PROPOFOL Cause?
Drug ineffective (1,627)
Anaphylactic shock (1,494)
Hypotension (1,388)
Off label use (889)
Anaphylactic reaction (862)
Cardiac arrest (758)
Bradycardia (470)
Tachycardia (464)
Propofol infusion syndrome (420)
Foetal exposure during pregnancy (389)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which PROPOFOL Alternatives Have Lower Cholestasis Risk?
PROPOFOL vs PROPOXYPHENE
PROPOFOL vs PROPOXYPHENE/ACETAMINOPHEN
PROPOFOL vs PROPRANOLOL
PROPOFOL vs PROPRANOLOL\PROPRANOLOL
PROPOFOL vs PROPYLENE GLYCOL