Does PYRAZINAMIDE Cause Leukopenia? 54 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 54 reports of Leukopenia have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 1.0% of all adverse event reports for PYRAZINAMIDE.
54
Reports of Leukopenia with PYRAZINAMIDE
1.0%
of all PYRAZINAMIDE reports
3
Deaths
20
Hospitalizations
How Dangerous Is Leukopenia From PYRAZINAMIDE?
Of the 54 reports, 3 (5.6%) resulted in death, 20 (37.0%) required hospitalization, and 6 (11.1%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 54 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Off label use (288)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which PYRAZINAMIDE Alternatives Have Lower Leukopenia Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB