Does PYRAZINAMIDE Cause Off label use? 288 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 288 reports of Off label use have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 5.2% of all adverse event reports for PYRAZINAMIDE.
288
Reports of Off label use with PYRAZINAMIDE
5.2%
of all PYRAZINAMIDE reports
62
Deaths
138
Hospitalizations
How Dangerous Is Off label use From PYRAZINAMIDE?
Of the 288 reports, 62 (21.5%) resulted in death, 138 (47.9%) required hospitalization, and 41 (14.2%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 288 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
Anaemia (234)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which PYRAZINAMIDE Alternatives Have Lower Off label use Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB