Does PYRIMETHAMINE Cause Cholestasis? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Cholestasis have been filed in association with PYRIMETHAMINE (Pyrimethamine). This represents 2.6% of all adverse event reports for PYRIMETHAMINE.
22
Reports of Cholestasis with PYRIMETHAMINE
2.6%
of all PYRIMETHAMINE reports
0
Deaths
17
Hospitalizations
How Dangerous Is Cholestasis From PYRIMETHAMINE?
Of the 22 reports, 17 (77.3%) required hospitalization, and 3 (13.6%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRIMETHAMINE. However, 22 reports have been filed with the FAERS database.
What Other Side Effects Does PYRIMETHAMINE Cause?
Off label use (126)
Nausea (121)
Vomiting (73)
Neutropenia (72)
Pancytopenia (66)
Rash (53)
Headache (45)
Death (39)
Thrombocytopenia (34)
Dizziness (33)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which PYRIMETHAMINE Alternatives Have Lower Cholestasis Risk?
PYRIMETHAMINE vs PYROTINIB
PYRIMETHAMINE vs QSYMIA
PYRIMETHAMINE vs QUETIAPINE
PYRIMETHAMINE vs QUINACRINE
PYRIMETHAMINE vs QUINAPRIL