Does RADIUM RA-223 DICHLORIDE Cause Pathological fracture? 44 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 44 reports of Pathological fracture have been filed in association with RADIUM RA-223 DICHLORIDE (Xofigo). This represents 0.9% of all adverse event reports for RADIUM RA-223 DICHLORIDE.
44
Reports of Pathological fracture with RADIUM RA-223 DICHLORIDE
0.9%
of all RADIUM RA-223 DICHLORIDE reports
12
Deaths
19
Hospitalizations
How Dangerous Is Pathological fracture From RADIUM RA-223 DICHLORIDE?
Of the 44 reports, 12 (27.3%) resulted in death, 19 (43.2%) required hospitalization, and 1 (2.3%) were considered life-threatening.
Is Pathological fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RADIUM RA-223 DICHLORIDE. However, 44 reports have been filed with the FAERS database.
What Other Side Effects Does RADIUM RA-223 DICHLORIDE Cause?
Prostatic specific antigen increased (449)
Hormone-refractory prostate cancer (441)
Death (376)
Anaemia (324)
Metastases to bone (315)
General physical health deterioration (308)
Fatigue (242)
Haemoglobin decreased (236)
Prostate cancer (234)
Nausea (221)
What Other Drugs Cause Pathological fracture?
DENOSUMAB (634)
LENALIDOMIDE (260)
DEXAMETHASONE (201)
ALENDRONATE (200)
ZOLEDRONIC ACID (185)
RISEDRONATE (110)
ADALIMUMAB (93)
LETROZOLE (87)
RITUXIMAB (87)
CYCLOPHOSPHAMIDE (85)
Which RADIUM RA-223 DICHLORIDE Alternatives Have Lower Pathological fracture Risk?
RADIUM RA-223 DICHLORIDE vs RALOXIFENE
RADIUM RA-223 DICHLORIDE vs RALTEGRAVIR
RADIUM RA-223 DICHLORIDE vs RALTITREXED
RADIUM RA-223 DICHLORIDE vs RAMELTEON
RADIUM RA-223 DICHLORIDE vs RAMIPRIL